Premier League leaders Manchester City will visit League One table-toppers Wigan in the fifth round of the FA Cup.
It is a repeat of the 2013 FA Cup final, which Wigan – then in the top flight – won 1-0.
Elsewhere, Manchester United will travel to fellow Premier League side Huddersfield or Championship club Birmingham, while Chelsea – beaten by Arsenal in the 2017 final – host Hull.
The ties will take place on the weekend of 17-18 February.
Should League Two side Newport County, the lowest-ranked team left in the competition, beat Tottenham in their fourth-round replay they will travel to either Championship side Millwall or Rochdale of League One.
Notts County’s replay with Premier League strugglers Swansea – which takes place on Tuesday, 6 February at 20:05 GMT – will be broadcast live on BBC One and online.
The winner of that game will travel to Sheffield Wednesday.
FA Cup fifth-round draw
Sheffield Wednesday v Notts County/Swansea
West Brom v Southampton
Chelsea v Hull
Leicester v Sheffield United
Huddersfield/Birmingham v Manchester United
Millwall/Rochdale v Newport County or Tottenham
Brighton v Coventry
Wigan v Manchester City